Understanding Marijuana and Glaucoma


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Marijuana has been explored as a possible way to lower eye pressure in glaucoma patients, but the science is complex. While cannabinoids may reduce intraocular pressure for short periods by interacting with the eye’s endocannabinoid system, this effect is temporary and may come with side effects that limit its practical use.
Dr. Gregory Cox, an ophthalmologist in Hamilton Township, NJ, stresses the importance of relying on proven treatments and open communication about all options. Serving patients from Mercer County and the Trenton region, Dr. Cox offers expert glaucoma treatment and surgery, comprehensive eye exams, laser vision correction, and more. His practice combines cutting-edge care with personalized attention, earning a 5-star average from over 900 reviews.

Glaucoma and Intraocular Pressure Connection
Glaucoma is usually associated with elevated IOP, which results from a buildup of aqueous humor, a clear fluid in the eye produced by the ciliary body. This fluid naturally drains through structures like the trabecular meshwork and Schlemm’s canal. When too much fluid accumulates, the pressure inside the eye increases, damaging the optic nerve and leading to vision loss if untreated.
Lowering IOP is critical in managing glaucoma. Studies such as the Ocular Hypertension Treatment Study (OHTS) and the Early Manifest Glaucoma Trial (EMGT) have shown significant evidence that reducing IOP slows the progression of glaucoma. In these studies, even a 25% reduction in IOP resulted in up to a 50% decrease in the risk of worsening glaucoma. Given this relationship, any treatment able to reduce IOP merits consideration, which is why marijuana’s potential role has generated interest.





Marijuana's Impact on IOP
Studies have consistently shown that marijuana can decrease IOP by approximately 20–30% for a period of 3–4 hours after administration. However, this short duration demands repeated dosing throughout the day to maintain lowered pressure, which introduces significant challenges and concerns.

Cannabinoid Mechanisms in the Eye





Benefits and Limitations: Research Findings
In controlled studies, marijuana has demonstrated a consistent ability to reduce intraocular pressure:
Comparison with Standard Treatments
Standard glaucoma therapies aim to maintain a consistent reduction in IOP across a full 24-hour cycle. These treatments include topical eye drops, laser therapy, and surgical interventions. Here’s how they compare with marijuana-based approaches:


Practical Limitations
and Challenges
Despite the documented IOP-lowering effect, several factors limit marijuana’s viability as a treatment for glaucoma:
Routes of Administration
Your Trusted Eye Doctor Serving Mercer County
Deciding whether marijuana is part of your glaucoma treatment plan means balancing its short-term benefits with possible side effects. Dr. Gregory Cox, serving Hamilton Township and Mercer County, guides patients through these considerations with clear, personalized advice. As an ophthalmologist, Dr. Cox provides expert glaucoma management, surgery, comprehensive eye exams, LASIK, and cataract care.
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If you’re looking for eye care that truly feels personal, you’ll find it right here in Hamilton Township at Gregory Cox, MD, conveniently located across from Robert Wood Johnson University Hospital. Our top-rated, board-certified ophthalmologist is known throughout Mercer County for his expertise and the genuine care he provides to every patient. That’s why patients and referring doctors from Trenton, Lawrence, Robbinsville, and beyond trust us for expert, personalized, and compassionate eye care.